The Malaysian Journal of Analytical Sciences Vol 17 No 2 (2013): 300 – 309

 

 

 

LIPID PEROXIDATION IN RAT LIVER USING DIFFERENT VEGETABLE OILS

 

(Peroksidaan Lipid Pada Hati Tikus yang Menggunakan Minyak Sayuran yang Berbeza)

 

Eqbal Dauqan^1*, Aminah Abdullah², Halimah Abdullah Sani¹

¹School of Biosciences and Biotechnology,

²School of Chemical Sciences and Food Technology,

Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor D.E., Malaysia

 

*Corresponding author: edouqan@yahoo.com

 

 

Abstract

The objective of the study was to evaluate the effect of different vegetable oils (Red Palm Olien (RPO), Palm Olein (PO), Corn Oil (CO) and Coconut Oil on lipid peroxidation of rat liver.  One hundred and thirty two Sprague Dawley male rats were randomly divided into two groups. The first group contains seventy two rats were divided into twelve groups of 6 rats per group and were treated with different concentrations of RPO (5%, 10% and 15%) for 2, 4 and 8 weeks.  The second group contains sixty male rats were randomly divided into ten groups of 6 rats per group and were treated with 15% of RPO, PO, CO and COC for 4 and 8 weeks. The results shows that after 8 weeks of treatment the malondialdehyde (MDA) value in RPO group was significantly lower (P≤0.05) than control or vegetable oils studied. These experiments suggested that red palm olein antioxidants present in rat diets may better attenuate peroxyl radical than other vegetable oil studied.

 

Keywords: : lipid peroxidation, malondialdehyde (MDA), vitamin E, β-carotene, vegetable oils, antioxidants

 

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