The Malaysian Journal of Analytical Sciences Vol 17 No 1 (2013): 50 – 58

 

 

 

ISOLATION AND CHARACTERIZATION OF COMPOUNDS FROM THE STEM BARK OF UVARIA RUFA (ANNONACEAE)

 

(Pemisahan dan Pencirian Sebatian dari Kulit Batang Uvaria rufa (Annonaceae))

 

Andi R. Rosandy¹, Laily B. Din¹, W .A. Yaacob¹*, Nik Idris Yusoff²,  I. Sahidin³, Jalifah Latip¹,

Syarul Nataqain⁴, Normah Mohd Noor⁴

 

¹School of Chemical Sciences and Food Technology, Faculty of Science and Technology,

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

²Pharmaceutical Chemistry Department, Kulliyyah of Pharmacy,

International Islamic University Malaysia, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia

³School of Pharmacy and Sciences,

Haluoleo University, Kendari, Indonesia

⁴Metabolomic Laboratory, Institute of Systems Biology (INBIOSIS),

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

 

*Corresponding author: wanyaa@ukm.my

 

 

Abstract

Isolation of compounds from methanol extract of the stem bark of Uvaria rufa has been conducted by using radial chromatography. Their structures were elucidated by UV, IR, NMR and mass spectroscopy, and by comparison with the literature. Seven compounds were isolated namely benzyl benzoate (1), caryophyllene oxide (2), glutinol (3), 5-hydroxy-7-methoxyflavone (4), 5-hydroxy-6,7-dimethoxyflavone (5), 2,5-dihydroxy-7-methoxyflavanone (6) and 5,7-dihydroxyflavanone (7). Separation of the caryophyllene oxide (2), glutinol (3) and 5,7-dihydroxyflavanone (7) from Uvaria rufa has never been reported.

 

Keywords: Annonaceae, Uvaria rufa, terpene, flavonoid

 

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