Malaysian
Journal of Analytical Sciences Vol 22 No 2 (2018): 303 - 310
DOI:
10.17576/mjas-2018-2202-16
EVALUATION OF DOSE SENSITIVITY RESPONSE VIA OPTICAL
CHARACTERISTICS FOR CRESOL RED-DYED POLYHYDROXYETHYLMETHACRYLATE GEL (PHEMAG)
(Penilaian
Respons Kepekaan Dos Melalui Ciri Optikal Bagi Kresol Merah-Dicelup
Polihidrosietilmetakrilik Gel (PHEMAG))
Nur Sha’adah Zainuddin1*, Fairuzdzah Ahmad Lothfy1,
Hartini Ahmad Rafaie1, Mazlini Mazlan2, Iskandar Shahrim Mustafa3, Azhar Abdul Rahman3
1Faculty of Applied Sciences,
Universiti Teknologi MARA Pahang, 26400 Bandar Tun
Abdul Razak Jengka, Pahang, Malaysia
2Faculty of Applied Sciences,
Universiti Teknologi MARA Tapah, 35400 Tapah, Perak,
Malaysia
3School of Physics,
Universiti Sains Malaysia, 11800 Minden, Pinang,
Malaysia
*Corresponding
author: nsz@pahang.uitm.edu.my
Received: 4
December 2016; Accepted: 1 December 2017
Abstract
A new
polymer gel blended with the acid base indicator of cresol red were prepared
consisted of 4%, 5% and 6% of monomer (2-Hydroxyethyl Methacrylate; HEMA) in
order to characterize the radiation induced changes known as cresol red
Polyhydroxyethylmethacrylate Gel (PHEMAG). Cresol red-dyed PHEMAG were prepared
consisted of gelatin, deionized water, HEMA, cresol red sodium salt stock
solution and ascorbic acid. The polymerization Cresol red-PHEMAG was studied
with 6 MV photon beam rates 300 Gy/min which received doses up to 40 Gy for the
reveletion sensitivity as a function of absorbed dose based on the physical
properties by using UV-Vis spectroscopy. It is indicated that 4% of HEMA
exhibited a greater sensitivity of the polymer gel dosimeter based on a
mathematical model of the fitting equation of the dose response curve. The
value of Do (sensitivity
parameter) for 4% of HEMA is the lowest about 42.373 Gy. The lower value of Do would cause the higher
radiosensitive of the matter which was actively reacted at the time of
exposure.
Keywords: absorbed dose, cresol red, photon beam,
polymer gel
Abstrak
Gel
polimer baru dicampur dengan penunjuk
asas asid kresol merah telah disediakan yang terdiri daripada 4%, 5% dan 6%
daripada monomer (2- hidrosietilmetakrilik; HEMA) untuk mencirikan radiasi
mendorong perubahan yang dikenali sebagai Kresol merah-dicelup Polihidrosietilmetakrilik Gel
(PHEMAG). Kresol merah – dicelup PHEMAG
telah dihasilkan terdiri daripada gelatin, air nyah ion, HEMA, stok larutan
kresol merah natrium garam dan asid askobik. Pempolimeran kresol merah PHEMAG
telah dikaji dengan pancaran foton 6 MV pada kadar yang berterusan 300 Gy/min
yang menerima dos sehingga 40 Gy untuk mendedahkan kepekaan sebagai fungsi dos
terserap berdasarkan sifat-sifat fizikal dengan menggunakan spektroskopi UV-Vis.
Ia menunjukkan bahawa 4% daripada HEMA menghasilkan kepekaan polimer gel
dosimeter yang lebih tinggi berdasarkan model persamaan matematik sesuai tindak
balas dos keluk. Nilai Do
(parameter sensitiviti) untuk 4% daripada HEMA adalah yang paling rendah
kira-kira 42.37 Gy. Nilai yang lebih rendah daripada Do akan menyebabkan radiosensitif jisim yang bertindak
balas secara aktif pada masa pendedahan.
Kata kunci: dos terserap, kresol merah, pancaran foton,
gel polimer
References
1. Schreiner, L. J., Olding, T. and McAuley, K.
B. (2010). Polymer gel dosimetry. Journal
of Physics: Conference Series, 250(1): 1-5.
2. Mattea, F., Romero, M. R, Vedelago, J.,
Quiroga, A., Valente, M. and Strumia, M. C. (2015). Molecular structure effects
on the post irradiation diffusion in polymer gel dosimeters. Applied Radiation and Isoptopes, 100:
101-107.
3. Vandescasteele, J. and De Deene, Y. (2013).
Evaluatioin of radiochromic gel dosimetry and polymer gel dosimetry in a
clinical dose verification. Physics in Medicine
and Biology, 58(18): 6241-6262.
4. MacDougall, N. D., Miquel, M. E. and Keevil,
S. F. (2014). Effects of phantom volume and shape on the accuracy of MRI BANG
gel dosimetry using BANG3TM. The
British Journal of Radiology, 81(986): 46-50.
5. Mattea, F., Chacon, D., Vedelago, J., Valente,
M. and Strumia, M. C. (2015). Polymer gel dosimeter based on itaconic acid. Applied Radiation and Isoptopes, 105:
98-104.
6. Doyan, A. (2009). Dose response and optical
properties of dyed poly vinyl alcohol-trichloroacetic acid polymeric blends
irradiated with gamma-rays. American
Journal of Applied Sciences, 6(12):
2071.
7. Beshir, W. B. (2013). Radiation sensitive
indicator based on tetrabromophenol blue dyed poly (vinyl alcohol). Radiation Phycis and Chemistry, 86: 129-135.
8. Saion, E., Doyan, A., Zainal Abidin, S., Azmi,
Z., Zulkifli, A., Mohd Zaki, A. and Karni, T. (2005). Changes in the optical
band gap and absorption edge of gamma-irradiated polymer blends. Journal of Applied Sciences, 5:
1825-1829.
9. Chanda, M. (2000). Advanced polymer chemistry: A
problem solving guide. Marcel Dekker: pp. 462-475.
10. Rozlan, A. A.,
Jaafar, M. S. and Rahman, A. A. (2011). A study of normoxic polymer gel
dosimeter using raman spectroscopy
analysis. International Conference on Biomedical Engineering and Technology, 11(2011): 19-23.
11. Ab Razak, N. N. A. N., Rahman, A. A.,
Kandaiya, S., Mustafa, I. S., Yahaya, N. Z. and Mahmoud, A. A. J. (2015).
Accuracy and precision of magat gel as a dosimeter. Material Science Research India,
12(1): 01-08.
12. Vergote, K. (2005). Development of polymer gel
dosimetry for applications in intensity-modulated radiotherapy. Department of
Radiotherapy and Nuclear Medicine, Faculty of Medicine and Health Sciences,
Gent, Belgium: pp. 20-21.
13. MacAuley, K. B. (2006). Fundamentals of
polymer gel dosimeters. Journal of
Physics: Conference Series, 56(1): 35.
14. Attix, F. H. (2008). Introduction to
radiological physics and radiation dosimetry. John Wiley & Sons: pp. 34-36.
15. Susilawati (2005). Radiation and temperature
effects on optical and electrical properties of dyed poly (vinyl alcohol)
organic composite containing chlorine. PhD dissertation, Universiti Putra
Malaysia.
16. Ebraheem, S., Eid, S. and Kovacs, A. (2002). A
new dyed poly (vinyl alcohol) film for high-dose applications. Radiation Physics and Chemistry, 63(3):
807-811.
17. Morris, S. and Williams, A. (2001).
Radiotherapy physics and equipment. Churchill Livingstone: pp. 28-30.
18. Abdel-Fattah, A. A., Hegazy, E. S. A. and El-Din, H. E. (2002). Radiation-chemical
formation of HCl in poly (vinyl butyral) films containing chloral hydrate for
use in radiation dosimetry. International
Journal of Polymeric Materials, 51(9): 851-874.