Malaysian Journal of Analytical Sciences Vol 17 No 3 (2013): 430 – 435

 

 

 

ISOLATION OF ASTILBIN FROM LEAVES OF CRATOXYLUM ARBORESCENS

 

(Pemencilan Komponen Astilbin dari Daun Cratoxylum arborescens)

 

Samsiah Jusoh^1,2, Zuriati Zakaria³ and Laily B. Din²*

 

¹Rice and Industrial Crop Research Centre,

Malaysian Agricultural Research and Development Institute (MARDI)

 P.O.Box 12301, 50774 Kuala Lumpur, Malaysia

² School of Chemical Sciences and Food Technology, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

³ Malaysia Japan Institute of Technology,

Universiti Teknologi Malaysia, 54100  Kuala Lumpur, Malaysia

 

*Corresponding author: lbdin@ukm.my

 

 

Abstract

Phytochemical studies was conducted on the leaves of Cratoxylum arborescens that has been collected from Post Brooke, Gua Musang, Kelantan, Malaysia. Traditionally, latex of the stem bark of C. arborescens is being used for the treatment of wound. Extraction of leaves of C. arborescens using organic solvents followed by purification using standard procedure of purification yielded known compound, astilbin. This compound was identified by NMR spectral data using various 2D-techniques and comparison with the literature data. Reports showed that this compound has a unique immunosuppressive activity, a selective inhibition against activated T lymphocytes. This characteristic of astilbin is beneficial for the treatment of human immune diseases.

 

Keywords: guttiferae, cratoxylum arborescens, astilbin, leaves, NMR

 

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